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HOW DOES BEAUTY SHOT protect your skin from free radical damage ?

Our skin is regularly exposed to a variety of environmental, chemical, and toxic agents that cause oxidative stress and inflammation in skin cells and lead to degeneration of our collagen matrix, thinning of the epidermis, reduced skin immunity and all the signs of premature aging.

The most common causes of oxidative stress to our skin are pollution, tiredness, sugar, junk food, smoking, alcohol and excessive UV exposure, and if the inflammation resulting from oxidative stress is allowed to continue unchecked, it can cause a cascade of cellular degeneration and accelerated skin aging.

Fortunately, there is a solution. Mother Nature’s natural antidotes to cellular oxidation are antioxidants : diverse molecules, usually in the form of pigments found in fruits and vegetables such as polyphenols and carotenoids that have the ability to neutralize free radicals in our skin and body and protect us from oxidative stress.

More and more, plant polyphenols are being identified as the best, most effective solution to increasing our skin’s defenses against oxidative stress and premature aging. In numerous research studies, plant polyphenols have been shown to shield our cells from oxidative stress, protect from sun damage, speed up cellular repair, boost cell immunity and protect skin against all types of disease and attack. Polyphenols have been shown to extend the active lifespan of skin cells and provide significant antioxidant, chemopreventive and immunosupportive effects to our skin cells.Polyphenols are key contributors to the process of cellular regeneration and collagen production. The concentrated, 100% natural fruit and plant extracts in BEAUTY SHOT provide a very high dose of broad-spectrum polyphenols to the skin, giving powerful protection against oxidative stress to all skin layers.

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HOW DOES BEAUTY SHOT stimulate collagen synthesis and smooth your skin.. ?

Collagen is the most abundant structural protein in the body. It is the ‘glue’ that holds our bodies together and represents about 70% of our skin and connective tissue when we are young. Natural collagen levels decrease with age and as a function of lifestyle choices (smoking, alcohol, fast-food & lack of sleep etc all accelerate collagen loss).

As we lose collagen – due to age or lifestyle choices, our body's natural ability to replace what has been lost also decreases. It is estimated that beyond the age of 25 the body's natural collagen levels typically reduce at a rate of 1.5% per year, leading to a 20% - 25% loss of collagen by the time we are 40 - or more if our skin is regularly exposed to free radicals and oxidative stress due to lifestyle choices.

As collagen production slows, we also lose elastin and hyaluronic acid and the structure of our connective tissue begins to break down; The less collagen we have, the thinner skin our skin becomes and the lesss it is able to maintain elasticity, retain moisture and protect itself against external attack. This leads to a thinner, drier complexion, wrinkles and the signs of aging.

Fortunately, numerous studies have demonstrated that combining flavonoids and natural Vitamin C with collagen supplementation leads to higher levels of collagen synthesis, as the antioxidants protect collagen-forming fibroblasts in our skin from oxidation and therefore allow them to focus their energy on regeneration – and better do their job.

BEAUTY SHOT contains pure, highly bioavailable Marine Collagen Type 1 combined with concentrated polyphenol antioxidants and natural Vitamin C. This combination helps to increase collagen synthesis and leads to an improvement in skin hydration, density, elasiticty and youthfulness1.

1 http://www.parmentier.de/gelatine/peptan4skin.pdf

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HOW DOES BEAUTY SHOT™ protect against gum disease.. ?

Periodontal or gum disease affects about 65 percent of teenagers and 75 percent of adults in the UK and America1. It is the most common disease in the world2and the leading cause of tooth loss in adults. Rates of gum disease have soared as it is fuelled by aggressive, pro-inflammatory bacteria in the mouth that thrive on refined carbohydrates and sugary foods ie, on a processed food diet. Symptoms of peridontal disease include sore, inflamed gums, gums that tend to bleed during brushing, a receding gumline, tooth decay and tooth loss.

BEAUTY SHOT™ is designed to prevent and heal gum disease by flooding your mouth with natural, probiotic antioxidants that nourish healthy, immunity-boosting oral bacteria. Probiotic antioxidants help optimize salival PH and discourage the proliferation of harmful bacteria, they reduce gum inflammation and actively protect against gum disease.

Probiotics such as the antioxidants in BEAUTY SHOT™ have been extensively studied for their health-promoting effects for many years. Probiotics (meaning ‘for life’) are micro-organisms shown to exert health promoting influences both on humans and animals. The main field of research has been the digestive tract and how probiotics can improve gut flora and boost overall immunity, however more and more research indicates that probiotics and probiotic antioxidants offer exactly the same benefits for oral health3.

Put simply, the presence of probiotic antioxidants encourages the growth of beneficial bacteria, such as Lactobacillus, in the mouth. Lactobacillus, already well known for its positive effect on gut flora, has the ability to rapidly colonize our mouth with ‘good‘ bacteria4and act as a ‘defenders’ of our oral health by preventing a wide range of undesirable, anaerobic bacteria including Streptococci5, Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis6, which all cause gum disease, from latching onto gum tissue and settling in.

The probiotic antioxidants in BEAUTY SHOT™ reduce inflammation by upregulating anti-inflammatory cytokines7and directly enhancing specific and general immune responses.89Probiotic antioxidants are furthermore thought to generally protect against infection by nourishing the growth of friendly bacteria that compete with pathogenic viruses & bacteria for binding sites on epithelial cells1011: ie, if there are enough friendly bacteria present, viruses find it hard to gain a foothold.

The broad spectrum polyphenols in BEAUTY SHOT™ are powerful antioxidants that act as «in-mouth gardeners» : they ‘weed-out’ harmful, anaerobic bacteria, enhance oral oxygenation and nourish beneficial, aerobic bacterial strains. The polyphenols, matcha green tea catchekins, mango carotenoids, raspberry anthocyanins and CoEnzyme Q10 in BEAUTY SHOT™ feed beneficial gum bacteria, reduce oral inflammation, help balance salival PH and increase all-round oral immunity.

By virtue of being a drink, BEAUTY SHOT™ is first absorbed in your mouth, where its probiotic antioxidants are assimilated both by your gums and by the blood vessels beneath your tounge. BEAUTY SHOT™ thus directly targets harmful bacteria in your mouth and acts to replace pro-inflammatory, disease-causing anaerobic bacteria with protective species. Its high concentration of probiotic antioxidants, in particular polyphenols, carotenoids, Vitamin C and CoEnzyme Q10, reduces cellular inflammation and boost gum resilience.

The high level of carotene antioxidants in BEAUTY SHOT also encourages the maintenance of healthy mucus membranes in the mouth, which further boosts gum immunity. Consumption of natural fruits rich in carotenes and Vitamin A is clinically proven to protect from oral cavity cancers12.

In addition to drinking a BEAUTY SHOT every day, another way to reduce your risk of gum disease is to drink plenty of pure water, to eat lots of fresh, raw fruits and vegetables, which supply your mouth with antioxidants in the most natural way and naturally « cleanse your teeth » and to brush your teeth regularly, particularly after a sugary or carbohydrate-rich meal.

Research indicates that the harmful bacteria that cause gum disease can spread very easily from the mouth all over the body, causing chronic inflammation wherever they go and triggering a series of immunologic responses that can launch the initiation of metabolic syndrome and degenerative disease13.

Gum diseases can increase your risk of all the most common degenerative diseases14including cancer and systemic infections15, heart disease16, respiratory diseases17, diabetes and conditions in general that shorten your lifespan18, so looking after your mouth and gums is an incredibly worthwhile health investment. BEAUTY SHOT is an enjoyable way to improve oral health and help protect against gum disease.

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HOW DOES BEAUTY SHOT promote healthy gut flora & lower blood sugar ?

Did you know that fat, overweight individuals have different bacteria in their gut from lean people.. ? Fascinatingly, slim people have an entirely different gut composition from overweight folk: Whereas slim individuals have large colonies of healthy gut bacteria and very little inflammation, overweight people have a lot of harmful bacteria and severe to chronic inflammation of the gut – inflammation which almost unavoidably causes rapid weight gain around the stomach.

The great news for anyone wishing to lose weight is that if you can change the balance of your gut flora – a process that happens naturally when you consume more high quality antioxidants (polyphenols, carotenes, Vitamin C...), then your level of visceral inflammation will reduce, as a result your body feels the need to develop fewer ‘protective’ fat cells - and you lose weight – even if your overall calorie intake remains the same!

Rates of obesity and diabetes are soaring all over the world due to a ‘pro-inflammatory’ fast food diet high in sugar, refined carbohydrates, factory farmed, antibiotic-rich meat and processed fats – and more recently, the inclusion of genetically modified ingredients has only made this process worse, as GM ingredients are in essence ‘foreign’ to our bodies and elicit and aggressive, highly inflammatory immune reponseiin our gut every time you eat them.As a result of this « inflammation epidemic » , over 65% of the US population today is considered overweight or obese, and the UK is following fast : 25% of the UK population is already classed as clinically obese and over 2.8 million adults in the UK suffer from diabetes.19What is more, the rate of obesity in the UK is forecast to accelerate rapidly within the next 25 years, leading to a sevenfold increase in the cost to the British health service of dealing with obesity by 2050. The wider cost to society of this almost entirely avoidable condition is anticipated to be around £45 billion.

We now know that a « processed food » diet (high in sugar, refined carbohydrates, hydrogenated fats, processed meat and GMO) negatively affects gut composition within days, killing off healthy bacteria and feeding explosions of harmful bacterial colonies in the gut. These harmful bacteria in turn produce pro-inflammatory cytokines and toxins which are seen as ‘poisons’ by our body, causing stress to increase sharply, raising cortisol levels and starting an inflammatory chain reaction in which our body tries to shield our organs from these toxins by wrapping them in protective layers of fat. Processed foods thus cause fat cells to grow & multiply even without increased calorie intakeii.

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Certain antioxidants, in particular the polyphenols found in BEAUTY SHOT have a powerfully probiotic action, and nourish the proliferation of healthy gut bacteria. Enough antioxidants in the gut can positively change the makeup of your gut bacteria within days, dislodging agressive, pro-inflammatory species and restoring healthy, probiotic bacteria such as lactobacillus, bifidobacteria and Gammaproteobacteria in the gut. This process of transforming your intestinal flora helps prevent inflammation, powerfully boosts your immunity and helps counteract many of the negative effects of a junk food diet. A 2011 study illustrates this point :

In this 2011 study, rats fed a specific form of lactobacillus (probiotic bacteria) put on significantly less weight than the control group who did not receive any lactobacillus, even though both groups of rats ate the same high-calorie diet. The rats fed lactobacillus had lower levels of silent inflammation, which has been associated with obesityiii, heart disease and cancer. Similarly, another study found that gut bacteria also impact the weight of human babies. This study found babies with high numbers of (probiotic) bifidobacteria appeared to be protected from excess weight gain. This may be one reason why breast-fed babies have a lower risk of obesity and are statistically slimmer than bottle fed inflants; as probiotic bifidobacteria flourish in the gut of breast-fed babiesiv.

BEAUTY SHOT™ is very rich in probiotic polyphenol antioxidants. One of its primary roles is thus to establish and safeguard a happy gut environment. As probiotic antioxidant polyphenols act as the “gardeners of the gut”, they ‘weed out’ harmful, anaerobic gut bacteria and feed the probiotic strains that digest food and eliminate harmful pathogens. The polyphenols (from Maqui berries, Blueberries, Raspberries, Acai berries, Curcumina, Matcha green tea etc.) thus help to rapidly restore an anti-inflammatory and resilient gut environment. Given that over 80% of our entire body’s immunity against disease is located in our digestive system, courtesy of these ‘probiotic’ bacteria, the act of boosting healthy bacterial levels in your gut is a key step towards a stronger immune system.

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Another super benefit of the Antioxidants in each BEAUTY SHOT is that they slow down entry of sugar from food into the blood stream. Antioxidants such as polyphenols and Vitamin C are able to block activity of a digestive enzyme called alpha-glucosidase. Alpha-glucosidase is a starch-digesting enzyme, and when it becomes active in the digestive tract it increases the breakdown of starches into sugars. These sugars get absorbed up into the bloodstream and can cause excessively high levels of blood sugar following a meal. (This process is called postprandial hyperglycemia.) By blocking activity of alpha-glucosidase, BEAUTY SHOT’s antioxidants may make it possible for persons with type 2 diabetes (or anyone experiencing issues with blood sugar regulation) to better manage their blood sugar levels. Therefore, if you drink a BEAUTY SHOT before consuming a high carb meal, the antioxidants in BEAUTY SHOT prevent a spike in insulin levels and cause a much gentler, steadier rise in blood sugar: High dose Polyphenols such as those found in each BEAUTY SHOT sachet regulate the amount of blood sugar and therefore of insulin produced after each meal: and lower blood sugar levels mean less inflammation, leading to smaller fat cells - and a slimmer you.

It is fascinating how Mother Nature packages up nutrition for humans. Fruits, which are high in fructose (fruit sugar), are packaged up with polyphenols that help your body metabolize the sugar you are consuming. When you eat fresh fruit, which contains both fructose and antioxidants, the antioxidant polyphenols in the fruit counteract the increase in blood sugar caused by the fructose, so your blood sugar only rises in a steady, ‘controlled’ manner. Remove the polyphenols from the equation and eating fructose by itself (such as in high fructose corn syrup) will cause blood sugar levels to soar. This is the general reason why fresh fruit helps reduce the risk of type 2 diabetes, and helps explain why it is so damaging to consume large amounts of fructose or other sugar without the matching polyphenols, as is common in our society.

Polyphenol flavonoids have extremely important functions within plants. They are part of the plant’s defense system against invasive infection, and their powerful immune support is transferred to humans by optimising the health of the bacteria in our gut. This is very important as we have roughly 10'000 times more bacteria in our gut than cells in our body, and these bacteria are responsible for 80 to 90 percent of our immunity against disease. Polyphenols help regulate cell functions within plants, and do the same for humans. They are naturally synthesized in higher amounts by plants when plants come under stress, which is why fruits that have to endure harsh environments also contain the highest level of antioxidants. They are also needed by humans in higher amounts when we are under stress, as happens when we are exposed to large amounts of free radicals. Higher levels of polyphenols help us to tolerate greater levels of stress without wear and tear.

It is that simple : drinking a polyphenol-loaded BEAUTY SHOT before any high carb or high sugar meal reduces the subsequent increase in blood sugar and protects your body from the associated inflammation and risk of Type 2 diabetes.

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It is worrying that stroke appears to be affecting people at a younger and younger age; this increased incidence being linked to poor diet, high cholesterol & high blood sugar, diabetes, obesity and a sedentary lifestyle. The polyphenol antioxidants in BEAUTY SHOT help prevent the oxidation of cholesterol in the blood. As these polyphenols travel around your body they interact with factors in your blood to protect the structure of your arteries and blood vessels. They have antioxidant, anti-inflammatory, anti-stress, and tissue rejuvenating properties.

As oxidation of cholesterol is an important factor in the development of cardiovascular disease, increasing the risk of heart attack, stroke and hardening of the arteries, a regular daily intake of BEAUTY SHOT is a simple way of supplying your body with the antioxidants it needs to keep arteries more supple and elastic andprovide direct health benefits to your circulatory system. A diet rich in natural polyphenols & flavonoids has a proven capacity toremove oxygen radicals from the blood and according to a study carried out by the Swedish Mammography Cohortv, actively to reduce the risk of cardiovascular disease.

1 Beck J, Garcia R, Heiss G, Vokonas PS, Offenbacher S.  1996.  Periodontal disease and cardiovascular disease. Journal of Periodontology 67(10 Suppl):1123-37.

3 Juliette Reeves <the health benefits of oral probiotics>

4Logan Buck. B, Altermann, E, Svingerud Tet al: Functional Analysis of Putative Adhesion Factors in Lactobacillus acidophilus NCFM APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Dec. 2005, p. 8344–8351

5Ishihara K, Miyakawa H, Hasegawa A et al: Growth inhibition of Streptococcus mutans by cellular extracts of human intestinal lactic acid bacteria. Infect Immun 1985;49:629-694

6Kõll P, Mändar R, Marcotte H, Leibur E, Mikelsaar M, Hammarström L. : Characterization of oral lactobacilli as potential probiotics for oral health. Oral Microbiol Immunol. 2008 Apr;23(2):139-47.

7Pessi, T., Sutas, Y., Hurme, M. and Isolauri, E. : Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG. Clin Exp Allergy 2000 30, 1804–1808.

8Perdigon, G. and Alvarez, S. (1992) Probiotics and the immune state. In Probiotics. The Scientific Basis ed. Fuller,

R. p, 146–180. London: Chapman and Hall.

9Ouwehand, A.C., Salminen, S. and Isolauri, E. (2002) Probiotics: an overview of beneficial effects. Antonie Van Leeuwenhoek 82, 279–289.

10DeSimone, C. : The adjuvant effect of yogurt on gamma interferon by Con-A stimulated human lymphocytes. Nutr Rep Int 1986 33, 419–433.

11O’Sullivan, M.G., Thornton, G., O’Sullivan, G.C. and Collins, J.K. : Probiotic bacteria: myth or reality.Trends Food

Sci Technol 1992 3, 309–314.

13National Institute of Craniofacial Research: www.nidcr.nih.gov/HealthInformation/DiseasesAndConditions/OralSystemicHealthConnection/OralSystemic.htm

14 Juliette Reeves: leading UK dental hygienist and nutritionist.

15Loos BG.: Systemic markers of inflammation in periodontitis. J Periodontol. 2005 Nov;76(11 Suppl):2106-15.

16Tenenbaum HC, Lai JY, Sheldermay A, Goldberg MB: Is there a link between periodontitis and cardiovascular disease? A report on the RCDSO Symposium, Oral Health: A Window To Systemic Disease. Feb 2 2005.

17Garcia RI: Epidemiologic Associations Between Periodontal Disease and Chronic Obstructive Pulmonary Disease. Ann Periodontol 2001 :6(1) 71-77.

18Saito T, Shimazaki Y, Kiyohara Y, et al. The severity of periodontal disease is associated with the development of glucose intolerance in non-diabetics: the Hisayama Study. J Dent Res 2004;83:485-90.

19 http://www.parliament.uk/edm/2010-12/1212

i http://articles.mercola.com/sites/articles/archive/2013/10/06/dr-huber-gmo-foods.aspx

ii http://articles.mercola.com/sites/articles/archive/2012/08/15/gut-flora-microscopic-organisms.aspx

iii British Journal of Nutrition 2011 Sep;106(6):887-95

iv American Journal of Clinical Nutrition March 2008: 87(3); 534-538